In 2005, Tautou starred in her first full Hollywood production, opposite Tom Hanks, in the film version of Dan Brown's best-selling novel The Da Vinci Code, directed by Ron Howard and released in May 2006.
She starred alongside Gad Elmaleh in Pierre Salvadori's Hors de prix (Priceless), released 13 December 2006.
I noticed that people became bigger than before because now they eat more cake and sweets and things like this that they didn't do in the past.
Her subsequent roles in the 1990s and 2000s included Le Libertin and Happenstance (2000).
Tautou achieved international recognition for her lead role in the 2001 film Amélie, which met with critical acclaim and was a major box-office success.
In 2004, she played in A Very Long Engagement, a romantic war film, co-written and directed by Jean-Pierre Jeunet starring Tautou.
It is a fictional tale about a young woman's desperate search for her fiancé who might have been killed in the Battle of the Somme, during World War I.
Grossing over $33 million in limited theatrical release, it is still the highest-grossing French-language film released in the United States.